LSDXOXO is praised throughout the dance world for his aggressive, sex-positive hybrid of ballroom, hip-house, breakbeat techno, and other styles of club music. His explosive DJ sets cleverly incorporate hooks and vocals from mainstream pop hits, as well as underground styles such as Baltimore club and hardcore. Through his involvement in club nights such as New York's GHE20G0TH1K and his own Berlin-based Floorgasm, LSDXOXO has stayed true to his mission to reclaim Black queer dancefloors. Since the early 2010s, he's collaborated with artists such as Cakes da Killa, Bbymutha, Kelela, and Shygirl, and released several well-received mixtapes, particularly 2018's Body Mods, as well as EPs like 2021's Dedicated 2 Disrespect and 2023's Delusions of Grandeur (D.O.G.).